OxyContin (oxycodone hydrochloride) can be an opioid drug employed for the management of reasonable to critical agony, normally for an extended time period.

To be able to stay clear of acquiring withdrawal indications, instruct clients not to discontinue OXYCONTIN without 1st speaking about a tapering plan with the prescriber [see DOSAGE AND ADMINISTRATION].

The in vitro details demonstrate that OXYCONTIN has physicochemical Attributes predicted to create abuse by using injection complicated. The information within the medical examine, together with assistance within the in vitro information, also indicate that OXYCONTIN has physicochemical Houses that are predicted to lessen abuse by using the intranasal route. On the other hand, abuse of OXYCONTIN by these routes, in addition to with the oral route, remains probable.

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The exercise of oxycodone hydrochloride tablets is largely due to the parent drug oxycodone. Oxycodone hydrochloride tablets are made to offer rapid launch of oxycodone.

In a scientific demo supporting the development of oxycodone hydrochloride tablets, way too several sufferers with reduced hepatic purpose were evaluated to review these probable differences.

Do not abruptly discontinue OXYCONTIN in individuals who may very well be physically dependent on opioids. Immediate discontinuation of opioid analgesics in sufferers who will be bodily depending on opioids has resulted in severe withdrawal symptoms, uncontrolled ache, and suicide.

The danger for extreme respiratory challenges is increased when you start this medication and following a dose boost, or if you're taking the incorrect dose/strength. Getting this medication with alcohol or other drugs that may cause drowsiness or respiration problems may well result in extremely serious Uncomfortable side effects, which includes Dying. Also, other medicines can influence the elimination of oxycodone from a entire body, which can affect how oxycodone performs.

“Drug-looking for” habits is very common in addicts and drug abusers. Drug-in check here search of techniques incorporate unexpected emergency phone calls or visits near the close of office hours, refusal to bear appropriate evaluation, tests or referral, repeated “reduction” of prescriptions, tampering with prescriptions and reluctance to deliver prior clinical information or Speak to details for other managing doctor(s).

To cut back the potential risk of respiratory depression, appropriate dosing and titration of OXYCONTIN are important [see get more info DOSAGE AND ADMINISTRATION]. Overestimating the OXYCONTIN dosage when converting people from One more opioid item can result in a deadly overdose with the very first dose.

Avoid having grapefruit or consuming grapefruit juice while applying this medication Unless of course your medical doctor or pharmacist says you may achieve this properly. Grapefruit can click here boost the prospect of Unintended effects with this medicine. Question your doctor or pharmacist for more specifics.

Separately titrate OXYCONTIN to the dosage that provides satisfactory analgesia and minimizes adverse reactions. get more info Constantly reevaluate individuals acquiring OXYCONTIN to evaluate the maintenance of pain Management, symptoms and signs and symptoms of opioid withdrawal, as well as other adverse reactions, and to reassess for the development of more info dependancy, abuse and misuse [see WARNINGS AND Safeguards].

Drug interactions may modify how your remedies operate or increase your possibility for severe side effects. This document does not have all possible drug interactions.

While it helps Lots of individuals, this medication may occasionally result in addiction. This threat could possibly be higher Should you have a substance use disorder (for instance overuse of or dependancy to drugs/Alcoholic beverages).